ea0017oc9 | Late effects | BSPED2008
Abdussalam A
, Elford C
, Jenny MEM
, Gregory JW
, Evans BAJ
Acute lymphoblastic leukaemia (ALL) is the most common childhood cancer. Given dramatic improvements in survival rate (>80%), long term quality of life is of rising concern. Skeletal complications including osteonecrosis (ON) are being reported more frequently, affecting up to 38% of children treated for ALL though the pathogenesis is unclear.The purpose of this study is to examine possible mechanisms causing ON. We hypothesize that polychemotherapy ...